Moser E, Marx F J, Gebauer A, Büll U
Rofo. 1981 Sep;135(3):267-74. doi: 10.1055/s-2008-1056874.
In 14 patients with renal cell carcinoma, not to be treated by nephrectomy, radionuclide angiography with 99mTc-DTPA (RNA) was employed before and after palliative tumor embolization. If RNA revealed remaining perfusion of the tumor, functional scintigraphy with 131J-hippurate was performed to detect and quantify residual function. Up to 16 months after embolization, 7 patients (50%) revealed neither residual perfusion nor function. In 5 patients (36%) remaining perfusion without functioning renal parenchyma and in 2 patients (14%) residual perfusion with additional function were found. In 4 cases (28%) a nuclear "tumor-halo" was imaged, describing a stripe of high radioactivity caused by capsular arteries surrounding the avascular tumor. RNA has proven to be a suitable non-invasive procedure for to blow-up of embolized renal cell carcinomas.
在14例不适合行肾切除术的肾细胞癌患者中,在姑息性肿瘤栓塞前后采用99mTc-DTPA放射性核素血管造影(RNA)。如果RNA显示肿瘤仍有灌注,则进行131J-马尿酸盐功能闪烁显像以检测和量化残余功能。栓塞后长达16个月,7例患者(50%)既无残余灌注也无功能。5例患者(36%)有残余灌注但无功能肾实质,2例患者(14%)有残余灌注且有额外功能。4例患者(28%)成像显示核“肿瘤晕”,表现为由无血管肿瘤周围的包膜动脉引起的高放射性条纹。RNA已被证明是一种适用于评估栓塞性肾细胞癌的非侵入性方法。