对照材料在人胰腺淀粉酶和唾液淀粉酶差异抑制试验中的适用性。

Suitability of control materials in the differential inhibition assay for human pancreatic and salivary amylase.

作者信息

O'Donnell M D, McGeeney K F

出版信息

Clin Chem. 1983 Mar;29(3):510-2.

Abstract

We investigated the behavior of 26 quality-control sera with the inhibitor method for differential amylase (EC 3.2.1.1) assay. We also studied the sensitivity to the wheat-derived inhibitor of pancreatic amylases from 10 different animals in comparison with human pancreatic and salivary amylase. The results indicate that only control materials containing human amylases can be measured accurately. The animal amylases (bovine, equine, porcine) used in many quality control sera are relatively insensitive to the inhibitor as compared with human pancreatic and salivary amylase.

摘要

我们采用抑制剂法对26份质量控制血清进行了鉴别淀粉酶（EC 3.2.1.1）检测的行为研究。我们还研究了10种不同动物的胰腺淀粉酶对小麦衍生抑制剂的敏感性，并与人类胰腺和唾液淀粉酶进行了比较。结果表明，只有含人类淀粉酶的对照材料才能被准确测量。与人类胰腺和唾液淀粉酶相比，许多质量控制血清中使用的动物淀粉酶（牛、马、猪）对该抑制剂相对不敏感。