H-2Dk产物与达卡巴嗪处理的H-2d淋巴瘤之间的免疫交叉反应性。
Immunological cross-reactivity between H-2Dk product and DTIC-treated H-2d lymphoma.
作者信息
Marelli O, Testorelli C, Canti G, Festenstein H, Nicolin A
出版信息
J Immunogenet. 1982 Dec;9(6):407-12. doi: 10.1111/j.1744-313x.1982.tb01002.x.
Abstract
The experiments reported here concern the characterization by techniques of in vitro cell-mediated immunity of the antigens induced by 5-(3,3' dimethyl-1-triazine)-imidazole-4-carboxamide (DTIC) on L1210, a chemically-induced lymphoma of DBA/2 mice (H-2d). This series of experiments with the DTIC-treated L1210 tumour show the presence of an 'H-2D'-like antigen which resembles the Dk gene product/s of the H-2k haplotype.
摘要
本文所报道的实验涉及通过体外细胞介导免疫技术对5-（3,3'-二甲基-1-三嗪）-咪唑-4-甲酰胺（DTIC）诱导的L1210抗原进行表征，L1210是DBA/2小鼠（H-2d）的一种化学诱导淋巴瘤。这一系列用DTIC处理的L1210肿瘤实验表明存在一种“H-2D”样抗原，它类似于H-2k单倍型的Dk基因产物。
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