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[烧伤患者的止血与肝素治疗。与预后和感染的关系。前激肽释放酶、α-2-巨球蛋白、抗凝血酶III、纤溶酶原和α-2-抗纤溶酶的血液水平模式]

[Hemostasis in burn patients and treatment with heparin. Relation to prognosis and infection. Pattern of blood levels of prekallikrein, alpha-2-macroglobulin, antithrombin III, plasminogen and alpha-2-antiplasmin].

作者信息

Hainaut J, Dhennin C, Guilbaud J

出版信息

Nouv Rev Fr Hematol (1978). 1982;24(6):375-81.

PMID:6188103
Abstract

In burnt patients with a fatal prognosis, the level of prekallikrein is initially low and further diminished. In burnt patients who survive, the initial decrease of the prekallikrein level is less pronounced and is progressively overcome, significantly by the sixth day. Moreover the decrease of the prekallikrein level occurs before and during clinical infection. In good prognosis patients, the level of alpha-2-macroglobulin remains low until day 20 and then increases in the noninfected patients while in fatal prognosis patients the level decreases. The level of antithrombin III and plasminogen is lower in fatal prognosis patients. These is no correlation between the level of antiplasmin and the outcome of burn injuries.

摘要

在预后不良的烧伤患者中,前激肽释放酶水平最初较低且进一步降低。在存活的烧伤患者中,前激肽释放酶水平的最初下降不太明显,并逐渐恢复,到第六天明显恢复。此外,前激肽释放酶水平的下降发生在临床感染之前及感染期间。预后良好的患者,α-2-巨球蛋白水平在第20天前一直较低,然后在未感染患者中升高,而在预后不良的患者中该水平下降。预后不良的患者抗凝血酶III和纤溶酶原水平较低。抗纤溶酶水平与烧伤结局之间无相关性。

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1
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Nouv Rev Fr Hematol (1978). 1982;24(6):375-81.
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