Skin fibroblasts in Huntington's disease. An electron microscopic study.
作者信息
Leonardi A, Mancardi G L, Gherardi G F, Cocito L, De Martini I, Tabaton M
出版信息
Eur Neurol. 1983;22(4):283-8. doi: 10.1159/000115572.
PMID:6224696
Abstract
Cultured skin fibroblasts of 3 patients with Huntington's disease (HD) and of 3 normal individuals have been examined by electron microscopy during the log phase of growth and at confluence. Though HD fibroblasts achieve higher maximal densities than controls, this is not associated with abnormal ultrastructural aspects of the cells. In particular, microfilaments and microtubules are identical in HD and normal fibroblasts.
摘要
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