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[左心室舒张末期压力功能参数的评估]

[Assessment of the functional parameter of left ventricular end-diastolic pressure].

作者信息

Jehle J

出版信息

Fortschr Med. 1984 Mar 22;102(11):313-7.

PMID:6232182
Abstract

In patients with an increase in enddiastolic pressure an impairment of left ventricular function is assumed. However, changes in left ventricular geometry (e.g. hypertrophy) or in elastic properties of the myocardium result in an increase in enddiastolic pressure, too. To differentiate the underlying mechanisms the elastic properties of the ventricle and myocardium, respectively, have to be determined. Our investigations show that the usually used determinations are not appropriate, if ventricular volumes are determined by means of angiography. The elastic properties can be calculated more exactly considering relaxation and thus the early filling phase of diastole. Moreover it is possible to perform this analysis by means of routinely determined hemodynamic parameters. So we propose a simple expression for the calculation of the elastic properties of the ventricle and get more information about the case of an increased enddiastolic pressure in clinical practise.

摘要

对于舒张末期压力升高的患者,假定存在左心室功能受损。然而,左心室几何形状的改变(如肥厚)或心肌弹性特性的改变也会导致舒张末期压力升高。为了区分潜在机制,必须分别测定心室和心肌的弹性特性。我们的研究表明,如果通过血管造影术测定心室容积,通常使用的测定方法并不合适。考虑到舒张期的松弛以及早期充盈阶段,可以更准确地计算弹性特性。此外,借助常规测定的血流动力学参数就可以进行这种分析。因此,我们提出了一个计算心室弹性特性的简单表达式,并在临床实践中获得了更多有关舒张末期压力升高情况的信息。

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