火鸡β-内啡肽和去乙酰化鲑鱼内啡肽的合成及放射受体结合活性
Synthesis and radioreceptor binding activity of turkey beta-endorphin and deacetylated salmon endorphin.
作者信息
Yamashiro D, Ferrara P, Li C H
出版信息
Int J Pept Protein Res. 1980 Jul;16(1):75-8. doi: 10.1111/j.1399-3011.1980.tb02938.x.
Abstract
Des-acetylated salmon endorphin and turkey beta-endorphin have been synthesized by the solid-phase method. Relative opiate activities in a radioreceptor binding assay are: human beta-endorphin, 100; des-acetylated salmon endorphin, 169; turkey beta-endorphin, 94. Thus, non-mammalian endorphins can show high activity in a mammalian assay system.
摘要
去乙酰化鲑鱼内啡肽和火鸡β-内啡肽已通过固相法合成。放射受体结合试验中的相对阿片活性为：人β-内啡肽100；去乙酰化鲑鱼内啡肽169；火鸡β-内啡肽94。因此，非哺乳动物内啡肽在哺乳动物检测系统中可表现出高活性。
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