[肝源性人血清铁蛋白的免疫抑制作用：α-2-HF球蛋白]
[Immunosuppressive effect of a human serum ferroprotein of hepatic origin: alpha-2-HF-globulin].
作者信息
Erard D, Rimbaut C, Auffredou M T, Galanaud P, Buffe D
出版信息
C R Acad Hebd Seances Acad Sci D. 1976 Sep 13;283(4):427-9.
PMID:62627
Abstract
alpha 2HF, a serum ferroprotein increased during some malignant diseases, displays a suppressive effect on in vitro antibody responses, whether T-independent or T-dependent. This effect is not related to the presence of iron, nor to the macroglobulin nature of the molecule. The immunosuppressive properties of alpha 2 HF might depend on its carbohydrate moeity.
摘要
α2HF是一种在某些恶性疾病期间血清铁蛋白增加的物质，它对体外抗体反应具有抑制作用，无论是非T细胞依赖性还是T细胞依赖性反应。这种作用与铁的存在无关，也与该分子的巨球蛋白性质无关。α2HF的免疫抑制特性可能取决于其碳水化合物部分。
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