Effect of transcutaneous electrotherapy on CSF beta-endorphin content in patients without pain problems.

作者信息

Salar Guiseppe, Job Ivo, Mingrino Salvatore, Bosio Angelo, Trabucchi Marco

机构信息

Department of Neurosurgery, University of Padua, Via Giustiniani, Padua, Italy Department of Pharmacology and Therapeutics, University of Brescia, Via Valsabbina 19, Brescia Italy.

出版信息

Pain. 1981 Apr;10(2):169-172. doi: 10.1016/0304-3959(81)90192-5.

To test the hypothesis of opiate-like peptide release after transcutaneous electrotherapy we measured beta-endorphin cerebrospinal fluid (CSF) content in 13 patients without pain problems. The results indicate a time dependent increase of CSF beta-endorphin in the group of patients studied. This fact suggests that the analgesic properties of the treatment may be ascribed to an involvement of the endogenous opiates system, independently from the basal clinical conditions of the patients.