Sugiyama T, Fujisawa T
J Cell Sci. 1978 Feb;29:35-52. doi: 10.1242/jcs.29.1.35.
A mutant strain (nf-I) of Hydra magnipapillata was isolated that contained no interstitial cells, nerve cells or nematocytes. This strain appeared spontaneously in a sexually inbred clone of hydra, and it was recognized by its inability to eat. When force-fed, however, it grew, multiplied by budding and regenerated. In this and in many other respects, nf-I was very similar to the interstitial cell-deficient strain produced by Campbell (1976) by means of colchicine. A chimera strain was produced by the reintroduction of interstitial cells from another strain into nf-I. The properties of nf-I, the chimera and other related strains were examined, and the possible roles that the interstitial cells and the nerve cells play in growth and morphogenesis of hydra are discussed.
分离出一种巨型乳头水螅的突变株（nf-I），该突变株不含间充质细胞、神经细胞或刺细胞。此菌株在水螅的有性近交克隆中自发出现，因其无法进食而被识别。然而，当强制喂食时，它会生长、通过出芽繁殖并再生。在这方面以及许多其他方面，nf-I与坎贝尔（1976年）通过秋水仙碱产生的间充质细胞缺陷株非常相似。通过将来自另一菌株的间充质细胞重新引入nf-I中产生了一种嵌合菌株。研究了nf-I、嵌合体和其他相关菌株的特性，并讨论了间充质细胞和神经细胞在水螅生长和形态发生中可能发挥的作用。
