Mills S A, Breyer R H, Johnston F R, Hudspeth A S, Marshall R B, Choplin R H, Cordell A R, Myers R T
J Thorac Cardiovasc Surg. 1982 Sep;84(3):367-72.
One case of primary malignant fibrous histiocytoma of the lung and two cases of that tumor in the mediastinum are reported. Primary malignant fibrous histiocytoma is rare in those areas, appearing more commonly in deep fascia and skeletal muscles of the extremities and torso and in the retroperitoneum. Most of the tumors contain both fibroblast-like and histiocyte-like cells; some contain pleomorphic giant cells and inflammatory cells. They are often confused with other sarcomas, and their true biologic potential is not clearly defined. Radiation appears to be a very useful adjunct to surgical therapy and was used in the cases reported here.
报告了1例原发性肺恶性纤维组织细胞瘤和2例纵隔该肿瘤。原发性恶性纤维组织细胞瘤在这些部位较为罕见,更常见于四肢和躯干的深筋膜、骨骼肌以及腹膜后。大多数肿瘤包含成纤维细胞样和组织细胞样细胞;有些含有多形性巨细胞和炎性细胞。它们常与其他肉瘤混淆,其真正的生物学潜能尚未明确界定。放疗似乎是手术治疗的一种非常有用的辅助手段,在本文报告的病例中使用了放疗。