绿头苍蝇唾液腺中的磷脂酰肌醇水解酶。
Phosphatidylinositol-hydrolysing enzymes in blowfly salivary glands.
作者信息
Irvine R F, Berridge M J, Letcher A J, Dawson R M
出版信息
Biochem J. 1982 Apr 15;204(1):361-4. doi: 10.1042/bj2040361.
Abstract
The salivary glands of adult blowflies (Calliphora erythrocephala) contain enzymes that hydrolyse phosphatidylinositol, predominantly by a Ca2+-independent deacylation, though a Ca2+-dependent phosphodiesterase (phospholipase C) activity could be detected. The deacylating enzymes could also hydrolyse phosphatidylcholine and phosphatidylethanolamine, and were secreted in the saliva. Homogenization of salivary glands prelabelled with [3H]inositol resulted in a rapid deacylation of the endogenous 3H-labelled phosphatidylinositol; this hydrolysis was unaffected by addition of 5-hydroxytryptamine to the homogenate.
摘要
成年红头丽蝇（Calliphora erythrocephala）的唾液腺含有能水解磷脂酰肌醇的酶，主要通过不依赖Ca2+的脱酰作用，不过也能检测到依赖Ca2+的磷酸二酯酶（磷脂酶C）活性。脱酰酶也能水解磷脂酰胆碱和磷脂酰乙醇胺，并分泌到唾液中。用[3H]肌醇预标记的唾液腺匀浆导致内源性3H标记的磷脂酰肌醇快速脱酰；向匀浆中添加5-羟色胺不影响这种水解作用。
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