Duffner P K, Cohen M E, Flannery J T
Cancer. 1982 Oct 15;50(8):1636-40. doi: 10.1002/1097-0142(19821015)50:8<1636::aid-cncr2820500829>3.0.co;2-6.
Data from the Connecticut Tumor Registry (1968-1979) were analyzed to determined whether referral patterns influenced survival rates in children with brain tumors. Two-hundred-seventy-eight children with brain tumors were identified. Less that one-third of the children received all their treatment at university cancer centers. An actuarial analysis of survival rates revealed that children with medulloblastomas treated solely at university cancer centers had projected five-year survival rates of 7.4%. Children with medulloblastomas treated solely at community hospitals had projected five-year survival rates of 29%. Children with brainstem gliomas treated at university cancer centers had projected five-year survival rates of 40% whereas of those children treated at community hospitals only one patient was alive at 13 months. No major differences in survival were identified among children with other tumor types. These data suggest that children with certain types of brain tumors may fare better when treated at university cancer centers.
对康涅狄格肿瘤登记处(1968 - 1979年)的数据进行了分析,以确定转诊模式是否会影响脑肿瘤患儿的生存率。共识别出278名脑肿瘤患儿。不到三分之一的患儿在大学癌症中心接受了所有治疗。生存率的精算分析显示,仅在大学癌症中心接受治疗的髓母细胞瘤患儿预计五年生存率为7.4%。仅在社区医院接受治疗的髓母细胞瘤患儿预计五年生存率为29%。在大学癌症中心接受治疗的脑干胶质瘤患儿预计五年生存率为40%,而在社区医院接受治疗的此类患儿中,只有一名患儿在13个月时存活。在其他肿瘤类型的患儿中未发现生存率有重大差异。这些数据表明,某些类型的脑肿瘤患儿在大学癌症中心接受治疗时可能预后更好。