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头孢甲肟在儿科领域的临床研究

[Clinical studies with cefmenoxime in the field of pediatrics].

作者信息

Takimoto M, Yoshioka H, Maruyama S, Sanae N, Nagamatsu I

出版信息

Jpn J Antibiot. 1982 Oct;35(10):2379-83.

PMID:6306289
Abstract

The present study was performed to evaluate the clinical effectiveness and safety of cefmenoxime (CMX), a new cephalosporin antibiotic for injection in the field of pediatrics. Thirty-one cases, including 2 cases with sepsis, 18 cases with respiratory tract infections and 7 cases with urinary tract infections, were given CMX at daily doses of 30 mg/kg to 125 mg/kg divided into 3 or 4 for 3 days to 13 days. Clinical responses were excellent in 16 cases, good in 9 cases and poor in 6 cases, the satisfactory response being 80.6%. No side effects and no abnormal laboratory findings relating to the drug were observed.

摘要

本研究旨在评估注射用新型头孢菌素抗生素头孢甲肟(CMX)在儿科领域的临床有效性和安全性。31例患者,包括2例败血症、18例呼吸道感染和7例尿路感染患者,给予CMX,日剂量为30mg/kg至125mg/kg,分3或4次给药,疗程3天至13天。临床反应优16例,良9例,差6例,满意反应率为80.6%。未观察到与药物相关的副作用和实验室检查异常。

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