[Electrophysiological study of frog eggs at different stages of development. III) Ionic currents activated by intense hyperpolarization and depolarization of the oocyte at the final stage of vitellogenesis].

In addition to K-selective channels, two kinds of voltage-dependent channels are present in the membrane of full-grown frog oocytes: 1) non-selective channels, activated by hyperpolarizing steps to potentials more negative than -80, -90 mV; 2) cationic channels, activated by depolarizing steps to potentials more positive than +30, +40 mV. The former are related to the inward rectification; the latter could contribute to the outward rectification of the I/V relationship. Therefore the membrane potential in full-grown oocytes tends to be maintained at a constant value due to the changes of permeability that follow possible potential variations occurring in both directions.