人体组织中腺苷受体的证据。
Evidence for an adenosine receptor in human tissues.
作者信息
Kurpis L, John D, Fox I H
出版信息
Adv Exp Med Biol. 1984;165 Pt A:497-500. doi: 10.1007/978-1-4684-4553-4_97.
PMID:6326488
Abstract
Our observations suggest that [3H] chloroadenosine, an adenosine receptor agonist, identifies binding sites in human placenta with characteristics of the high affinity, adenosine receptor. The binding is time dependent, reversible and saturable. The potency series of adenosine receptor methylxanthine antagonists in displacing [3H] chloroadenosine is appropriate.
摘要
我们的观察结果表明，[3H]氯腺苷，一种腺苷受体激动剂，可识别具有高亲和力腺苷受体特征的人胎盘结合位点。这种结合具有时间依赖性、可逆性和饱和性。腺苷受体甲基黄嘌呤拮抗剂在置换[3H]氯腺苷时的效价顺序是合适的。
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