[In vitro treatment of human bone marrow in the elimination of tumor cells: initial experiences with cytotoxic monoclonal anti-T-cell antibody LAU-A1].

The authors present evidence that elimination of tumor cells in the bone marrow is essentially possible by in vitro purging with the monoclonal anti-T-cell antibody LAU-A1 and complement; this procedure does not interfere with regeneration capacity of stem cells. These findings have an important bearing with regard to candidates for autologous bone marrow transplantation.