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[桥小脑角表皮样囊肿。6例]

[Epidermoid cysts of the cerebellopontile angle. 6 cases].

作者信息

Fischer G, Bret P, Hor F, Pialat J, Massini B

出版信息

Neurochirurgie. 1984;30(6):365-72.

PMID:6335572
Abstract

6 cases of cerebello-pontine angle (CPA) epidermoid cysts were encountered from 1970 up to 1983. This series accounts for 3,3% of 177 CPA tumours operated on during the same period. Epidermoid cysts result from heterotopia of ectoblastic tissue and CPA is their most frequent site of development. The wall of the cyst is composed of a stratified squamous epithelium. The inside of the cyst is filled with soft waxy material resulting from the desquamation of keratin of the cyst wall. Macroscopically, the cyst is extensive and usually closely attached to the brain stem, cranial nerves and vessels. The commonest clinical picture is that of a trigeminal neuralgia usually typical of tic douloureux. Plain x-ray films of the skull disclose no abnormalities. Air encephalography was performed in an early case: it showed an obliteration of the cerebello pontine cistern by the cyst mass, with no air injection of the tumor as mentioned elsewhere. Computerized tomography made other procedures obsolete in our 4 latest cases: it showed a non-enhancing low-density mass filling the CPA. Hypodensity characteristics can make differentiation from dermoïd and arachnoid cysts. In a patient, auditory evoked response were lengthened bilaterally and suggested a brain stem compression rather than a cochlear nerve involvement. Operative treatment was performed in all of our 6 patients through a suboccipital craniotomy with the aid of the operative microscope. The aim of surgery should be, whenever possible, total removal of the capsule. A partial section of the fifth nerve is not needed. No patient died postoperatively.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1970年至1983年期间共收治6例桥小脑角(CPA)表皮样囊肿。该系列病例占同期177例接受手术的CPA肿瘤的3.3%。表皮样囊肿由外胚层组织异位形成,CPA是其最常见的发生部位。囊肿壁由复层鳞状上皮组成。囊肿内部充满了因囊肿壁角质层脱屑而产生的柔软蜡样物质。肉眼可见,囊肿范围广泛,通常与脑干、脑神经和血管紧密相连。最常见的临床表现是典型的三叉神经痛,通常为痛性抽搐。头颅平片未发现异常。早期有一例进行了气脑造影:显示囊肿肿块使桥小脑池闭塞,未出现如其他文献所述的肿瘤内注入气体的情况。在我们最近的4例病例中,计算机断层扫描使其他检查方法过时:它显示一个低密度肿块填充CPA,低密度特征可与皮样囊肿和蛛网膜囊肿相鉴别。有一例患者双侧听觉诱发电位延长,提示脑干受压而非耳蜗神经受累。我们所有6例患者均通过枕下开颅术并借助手术显微镜进行了手术治疗。手术的目的应尽可能是完整切除包膜。无需部分切断第五神经。术后无患者死亡。(摘要截短至250字)

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1
[Epidermoid cysts of the cerebellopontile angle. 6 cases].[桥小脑角表皮样囊肿。6例]
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引用本文的文献

1
Has management of epidermoid tumors of the cerebellopontine angle improved? A surgical synopsis of the past and present.桥小脑角表皮样肿瘤的治疗有改善吗?过去与现在的手术概述。
Skull Base. 2008 Mar;18(2):85-98. doi: 10.1055/s-2007-991108.
2
Trigeminal neuralgia related to cerebellopontine angle tumors.与桥小脑角肿瘤相关的三叉神经痛
Neurosurg Rev. 1996;19(4):237-41. doi: 10.1007/BF00314838.
3
Radiologic evaluation of epidermoid cyst.表皮样囊肿的放射学评估。
J Natl Med Assoc. 1987 Feb;79(2):209-12.
4
Parapontine epidermoid tumours presenting as trigeminal neuralgias: anatomical findings and operative results.表现为三叉神经痛的脑桥旁表皮样肿瘤:解剖学发现及手术结果
Acta Neurochir (Wien). 1991;110(3-4):116-9. doi: 10.1007/BF01400677.