Pierre-Kahn A, Renier D, Sainte-Rose C, Hirsch J F
Neurochirurgie. 1983;29(5):359-63.
From 1971 to 1982, the authors saw 41 patients who presented lumbo sacral lipomas with spina bifida; 9 remained outpatients and had regular clinical follow up; the other 32 were operated on; 1 was lost sight of, shortly after the operation. 40 patients were then regularly followed; of these, 15 (37%) developed neurological deficits (14 before and 1 long after surgery). Intraspinal lipomas were classified into 2 groups: group I (18 cases), when the lipomas displaced but did not include the lumbo sacral roots; group II (14 cases) when it included most or all of these roots. Despite an inevitably less satisfactory liberation of the spinal cord in the group II, post operative results were not significantly different in the 2 groups. Comparing the post operative results of this series to others in the literature, the authors come to the following 3 conclusions: 1) these operations are benign; 2) they are all the more effective when the neurological deficits are either recent or evolutive, and 3) they protect most of the patients from eventual neurological deterioration. Therefore the authors agree that patients with lumbo sacral lipomas should be operated on at the onset of neurological deficits but also recommend early intervention, even in the absence of any neurological disturbance.
1971年至1982年期间,作者共诊治了41例患有脊柱裂的腰骶部脂肪瘤患者;9例为门诊患者,接受定期临床随访;其余32例接受了手术治疗;其中1例在术后不久失访。随后对40例患者进行了定期随访;其中15例(37%)出现神经功能缺损(14例在术前出现,1例在术后很久出现)。脊髓内脂肪瘤分为两组:第一组(18例),脂肪瘤移位但未累及腰骶神经根;第二组(14例),脂肪瘤累及大部分或全部这些神经根。尽管第二组脊髓松解效果必然不太理想,但两组术后结果并无显著差异。将本系列的术后结果与文献中的其他结果进行比较,作者得出以下三点结论:1)这些手术是良性的;2)当神经功能缺损为近期出现或进行性发展时,手术效果更佳;3)手术可使大多数患者避免最终的神经功能恶化。因此,作者同意腰骶部脂肪瘤患者应在出现神经功能缺损时进行手术,但也建议即使在没有任何神经功能障碍的情况下也应尽早干预。