Defective neutrophil mobilization to skin chambers in cancer patients.
作者信息
Frumento G, Bonvini E, Minervini F, Dallegri F, Patrone F, Sacchetti C
出版信息
J Cancer Res Clin Oncol. 1984;107(1):53-6. doi: 10.1007/BF00395491.
Abstract
The in vivo migration of neutrophils was evaluated in patients affected by epithelial carcinoma using the quantitative skin-chamber technique. The results demonstrated a significant impairment of the patients' neutrophil migration, which was reduced to approximately 4% of that of the controls. Patients' sera were able to inhibit the chemotactic responsiveness of normal neutrophils in vitro. It is therefore suggested that the defective in vivo migration of neutrophils in cancer patients is related to the presence of humoral cell-directed inhibitory activity. This defect of neutrophil function might contribute to the host-defense impairment of carcinoma patients.
摘要
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1
QUANTITATIVE STUDIES OF THE LOCAL EXUDATIVE CELLULAR REACTION IN ACUTE LEUKEMIA.
J Clin Invest. 1964 Mar;43(3):425-30. doi: 10.1172/JCI104927.
2
Polymorphonuclear neutrophil function in malignant lymphomas and effects of splenectomy.
Cancer. 1980 Feb;45(3):469-75. doi: 10.1002/1097-0142(19800201)45:3<469::aid-cncr2820450310>3.0.co;2-2.
3
Serum-associated inhibition of neutrophil Fc receptors in cancer patients.
J Natl Cancer Inst. 1981 Oct;67(4):803-7.
4
Removal of stratum corneum in vivo: an improvement on the cellophane tape stripping technique.
J Invest Dermatol. 1973 Feb;60(2):84-7. doi: 10.1111/1523-1747.ep12724159.
5
Antiinflammatory effects of murine malignant cells.
Proc Natl Acad Sci U S A. 1974 Oct;71(10):4052-6. doi: 10.1073/pnas.71.10.4052.
6
Cell-mediated cytotoxicity, allograft rejection, and tumor immunity.
Adv Immunol. 1974;18:67-132. doi: 10.1016/s0065-2776(08)60308-9.
7
Possible role of macrophage mediated nonspecific cytotoxicity in tumour resistance.
Nat New Biol. 1972 Jan 12;235(54):48-50. doi: 10.1038/newbio235048a0.
8
9
Tumor cells cytotoxicity by granulocytes from peripheral blood of tumor-bearing mice.
J Natl Cancer Inst. 1978 Mar;60(3):687-91. doi: 10.1093/jnci/60.3.687.
10
Abnormal monocyte chemotaxis in patients with breast cancer: evidence for a tumor-mediated effect.
J Natl Cancer Inst. 1978 Apr;60(4):737-40. doi: 10.1093/jnci/60.4.737.
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