人乳腺癌细胞中性类固醇结合血浆蛋白的免疫组织化学检测

Immunohistochemical detection of the sex steroid-binding plasma protein in human mammary carcinoma cells.

作者信息

Tardivel-Lacombe J, Egloff M, Mazabraud A, Degrelle H

出版信息

Biochem Biophys Res Commun. 1984 Jan 30;118(2):488-94. doi: 10.1016/0006-291x(84)91329-9.

Abstract

A sex steroid-binding plasma protein-like antigen has been detected in human mammary carcinoma cells. A monospecific antiserum was used, and this protein was located mainly on the cytoplasmic membranes. These results are in agreement with a recent hypothesis according to which steroid hormones could be carried into cells by specific binding plasma proteins.

摘要

在人乳腺癌细胞中检测到一种类似性类固醇结合血浆蛋白的抗原。使用了一种单特异性抗血清，这种蛋白主要位于细胞质膜上。这些结果与最近的一种假说相符，根据该假说，类固醇激素可能通过特异性结合血浆蛋白被带入细胞。