Kern R Z, Houpt J B
Can Med Assoc J. 1984 Apr 15;130(8):1025-8.
Vertebral osteomyelitis represents a diagnostic challenge to the clinician. Two cases of pyogenic vertebral osteomyelitis occurring weeks to months after a urinary tract infection with Escherichia coli are described. The rarity and subtle clinical presentation of this condition, the presence of pre-existing degenerative arthritic changes, and delayed appearance of radiologic signs of progression to destructive osteomyelitis contributed to a significant delay in diagnosis. Increased awareness of vertebral osteomyelitis as a clinical entity combined with information from radionuclide scanning may permit earlier detection of this condition.
脊椎骨髓炎对临床医生来说是一项诊断挑战。本文描述了两例在大肠杆菌引起的尿路感染数周或数月后发生的化脓性脊椎骨髓炎病例。这种疾病的罕见性和微妙的临床表现、先前存在的退行性关节炎改变以及进展为破坏性骨髓炎的放射学征象出现延迟，导致诊断出现显著延迟。提高对脊椎骨髓炎作为一种临床实体的认识，并结合放射性核素扫描的信息，可能有助于更早地发现这种疾病。
