传染性单核细胞增多症青少年中β溶血性链球菌性咽炎的发病率。

Incidence of beta hemolytic streptococcal pharyngitis in adolescent with infectious mononucleosis.

作者信息

Collins M, Fleisher G R, Fager S S

出版信息

J Adolesc Health Care. 1984 Apr;5(2):96-100. doi: 10.1016/s0197-0070(84)80006-6.

Abstract

Reports on the incidence of beta-hemolytic group A streptococci (BHGAS) in the pharynx of patients with infectious mononucleosis (IM) have varied from 3% to 33%. To ascertain the rate of infection, we prospectively performed serial throat cultures and determined anti-streptococcal antibody titers on 45 students with confirmed IM by Epstein-Barr virus-specific serology. One hundred healthy control students had throat cultures for comparison. The rate of recovery of BHGAS was similar in patients with IM (4%) and controls (3%). No students with IM had a fourfold rise of anti-streptococcal antibodies. We conclude that routine culture for BHGAS and/or treatment with antibiotic agents is not indicated in all patients with IM.

摘要

关于传染性单核细胞增多症（IM）患者咽部A组β溶血性链球菌（BHGAS）感染率的报道从3%到33%不等。为确定感染率，我们对45名经爱泼斯坦-巴尔病毒特异性血清学确诊为IM的学生进行了前瞻性系列咽拭子培养，并测定了抗链球菌抗体滴度。100名健康对照学生进行了咽拭子培养以作比较。IM患者（4%）和对照组（3%）中BHGAS的检出率相似。没有IM患者的抗链球菌抗体呈四倍升高。我们得出结论，并非所有IM患者都需要常规培养BHGAS和/或使用抗生素治疗。