Adler M W
Br J Vener Dis. 1978 Feb;54(1):15-23. doi: 10.1136/sti.54.1.15.
The current methods of treatment and reporting are described. The most common form of treatment for gonorrhoea in men and women was a single dose of oral ampicillin, usually 2 g. In proportionately more of the clinics treating women, treatment was given over several days. The wide use of ampicillin represents a marked change in treatment practice during the last decade. Procaine penicillin was the most commonly used parenteral preparation. The two dosages used most often for men were 1.2 and 2.4 megaunits. In women the commonest regimen was 2.4 megaunits and again there was a tendency for treatment to be given over several days. Epidemiology treatment was used widely and in one-third of clinics this occurred without confirmation that the patient was a true contact. Consultants used varying diagnoses on the quarterly returns for patients treated epidemiologically in whom the smears and/or cultures were negative. Most clinics classified these cases as 'other conditions requiring treatment' (D2) but as many as 19% of clinics designated these cases as being 'true' gonorrhoea. It is suggested that this results in an overestimate of the number of cases of 'real' gonorrhoea treated in England and Wales.
文中描述了当前的治疗方法及报告情况。男性和女性淋病最常见的治疗方式是单次口服氨苄西林,通常为2克。在治疗女性的诊所中,有较大比例的患者接受了数天的治疗。氨苄西林的广泛使用代表了过去十年治疗方法的显著变化。普鲁卡因青霉素是最常用的注射制剂。男性最常使用的两种剂量分别为120万单位和240万单位。女性最常见的治疗方案是240万单位,同样有在数天内进行治疗的趋势。广泛采用了流行病学治疗方法,在三分之一的诊所中,即使未确认患者是真正的接触者也采用了这种方法。对于涂片和/或培养结果为阴性的接受流行病学治疗的患者,顾问们在季度报告中使用了不同的诊断。大多数诊所将这些病例归类为“其他需要治疗的病症”(D2),但多达19%的诊所将这些病例认定为“真正的”淋病。这表明这导致了对英格兰和威尔士治疗的“真正”淋病病例数量的高估。