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[新喀里多尼亚产肠毒素大肠杆菌所致腹泻。流行病学和细菌学方面]

[Diarrhea due to enterotoxigenic Escherichia coli in New Caledonia. Epidemiology and bacteriologic aspects].

作者信息

Germani Y, Dassy B, Moreau J P

出版信息

Bull Soc Pathol Exot Filiales. 1984 Jul-Aug;77(4):423-32.

PMID:6391708
Abstract

Three types of Escherichia coli play important roles in the etiology of acute diarrhoea. Depending on the pathogenicity mechanisms involved, the E. coli intestinal strains can be divided into enteropathogenic (EPEC), enteroinvasive (EIEC) and enterotoxigenic (ETEC) strains. We have studied ETEC in New-Caledonia. In one year 53 strains were isolated. ETEC are isolated frequently during the wet season in melanesian children with a law hygiene level. A correlation has been established between the fermentation of the rhamnose and the production of heat-stable toxin (ST). All the strains ST+ had the same antibiotype (8 resistances). The strains producing heat-labile toxin (LT) had various antibiotypes. Eleven O serotypes have been identified and the 078 is the most frequent. An another plan we have identified serotypes found in Australia and in the SE Asian.

摘要

三种类型的大肠杆菌在急性腹泻的病因学中起重要作用。根据所涉及的致病机制,大肠杆菌肠道菌株可分为肠致病性(EPEC)、肠侵袭性(EIEC)和产肠毒素性(ETEC)菌株。我们在新喀里多尼亚对ETEC进行了研究。在一年时间里分离出了53株菌株。在卫生水平较低的美拉尼西亚儿童的雨季期间,ETEC经常被分离出来。已确定鼠李糖发酵与热稳定毒素(ST)的产生之间存在相关性。所有ST+菌株具有相同的抗微生物型(8种耐药性)。产生不耐热毒素(LT)的菌株具有不同的抗微生物型。已鉴定出11种O血清型,其中O78最为常见。另一方面,我们已经鉴定出在澳大利亚和东南亚发现的血清型。

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