[Effect of growth phase and composition of the medium on the rate of biosynthesis of NADH: rubredoxin oxidoreductase in Clostridium acetobutylicum].

Among the three strains of Clostridium acetobutylicum we investigated: NRRL 592, NCIB 619 and ATCC 824, only the last was shown to contain a NADH: rubredoxin oxidoreductase activity. We report that the biosynthesis rate of this enzyme fluctuated in the proportions of 1 to 50 according to the growth phase and medium composition. These variations reflect a mode of regulation adjusted to the metabolism of bacteria.