Influence of 2-mercaptopropionylglycine on DMBA-induced biochemical changes in regenerating mouse liver: II. Glucose-6-phosphate dehydrogenase, malic enzyme DNA, and protein.

Present investigation documents the influence of 2-mercaptopropionylglycine, a hepatropic detoxicant, on glucose-6-phosphate dehydrogenase, malic enzyme, DNA, and total protein contents in regenerating mouse liver exposed to a chemical carcinogen--DMBA. DMBA, when given alone, decreases the levels of these macromolecular constituents in the regenerating liver. When MPG is given with DMBA, the levels of these, except that of G6P-DH, are maintained at control levels.