Bibro M C, Fourcroy J L, Eil C
Fertil Steril. 1984 Oct;42(4):655-8. doi: 10.1016/s0015-0282(16)48156-2.
A 23-year-old male presented with primary infertility, normal male phenotype, and azoospermia. He had normal basal T, FSH, and LH levels and responded normally to clomiphene citrate stimulation. He also had normal androgen receptors in cultured pubic skin fibroblasts. A testis biopsy showed only Sertoli cells and no evidence of seminiferous tubule damage, lacking the fibrosis or Leydig cell hyperplasia usually seen in SCOS. This case of SCOS, combined with those previously reported, suggests that the etiology of SCOS is heterogeneous, with a single common end point, or that it is a single process that has been studied at different developmental stages by different investigators.
一名23岁男性因原发性不育前来就诊，其具有正常男性表型且无精子症。他的基础睾酮（T）、促卵泡生成素（FSH）和促黄体生成素（LH）水平正常，对枸橼酸氯米芬刺激反应正常。他培养的耻骨皮肤成纤维细胞中的雄激素受体也正常。睾丸活检仅显示支持细胞，没有生精小管损伤的证据，也没有通常在唯支持细胞综合征（SCOS）中所见的纤维化或间质细胞增生。该例SCOS病例，结合先前报道的病例，提示SCOS的病因是异质性的，具有单一共同终点，或者它是一个在不同发育阶段被不同研究者研究的单一过程。
