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亨廷顿舞蹈症

Huntington's disease.

作者信息

Paulson G W

出版信息

Am Fam Physician. 1980 Jul;22(1):91-3.

PMID:6446233
Abstract

Huntington's disease (chorea) is characterized by abnormal movements and dementia. It is transmitted as an autosomal dominant trait. The age of onset is variable, but there is a tendency for the symptoms to begin at about the same age in affected members of a family. Haloperidol is commonly used to treat the chorea; there is no treatment for the dementia. Recent research has suggested abnormalities in tissue levels of gamma-aminobutyric acid. Treatment is supportive and should be provided by the family physician.

摘要

亨廷顿舞蹈症(舞蹈病)的特征是异常运动和痴呆。它作为常染色体显性性状遗传。发病年龄因人而异,但一个家庭中受影响成员的症状往往在大致相同的年龄开始出现。氟哌啶醇常用于治疗舞蹈病;痴呆症尚无治疗方法。最近的研究表明γ-氨基丁酸的组织水平存在异常。治疗以支持性治疗为主,应由家庭医生提供。

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