King D R, Savrin R, Boles E T
J Pediatr Surg. 1980 Aug;15(4):553-7. doi: 10.1016/s0022-3468(80)80772-x.
Sixty-four infants with gastroschisis have been managed in the 9-yr period, 1970-1979, with four postoperative deaths. The silo technique has been the standard method of management in this series, permitting initial expansion of the abdominal cavity without increased abdominal pressure and respiratory embarassment. Removal of the silo and complete closure of the abdominal wall deficit were possible 5-12 days later. A high proportion of the infants were below 2500 g in weight at birth (61%); and although 3 of the 4 postoperative deaths occurred in the low birth weight group, this did not appear to be a factor in mortality. Associated anomalies occurred in 25 of the 64, but only the coincident intestinal atresias (6) were of major significance. These additional anomalies were not responsible for deaths. Two deaths occurred from problems dating from birth, one from aspiration and the second from sepsis. The other two resulted from postoperative complications resulting in infarction of the midgut. Both were caused in part by failure to adequately enlarge the abdominal wall defect at the time of the initial procedure. Other postoperative complications were relatively few. Although all required intravenous nutritional support, the long term results in terms of growth and development and of intestinal function were quite satisfactory.
1970年至1979年的9年间,共收治64例腹裂患儿,术后死亡4例。在本系列病例中,“袋状缝合法”一直是标准的治疗方法,它能在不增加腹压和不影响呼吸的情况下使腹腔初步扩张。5至12天后可拆除“袋状缝合”并完全闭合腹壁缺损。出生时体重低于2500克的婴儿比例较高(61%);虽然4例术后死亡中有3例发生在低体重组,但这似乎不是导致死亡的因素。64例中有25例伴有其他畸形,但只有同时存在的肠闭锁(6例)具有重要意义。这些额外的畸形并非导致死亡的原因。2例死亡源于出生时就存在的问题,1例死于吸入,另1例死于败血症。另外2例死于术后并发症导致的中肠梗死。两者部分是由于初次手术时未能充分扩大腹壁缺损所致。其他术后并发症相对较少。虽然所有患儿都需要静脉营养支持,但在生长发育和肠道功能方面的长期结果相当令人满意。