Weiss S, Zyskind Z, Rosenthal T, Arditti A J, Laniado S
Z Rheumatol. 1980 May-Jun;39(5-6):190-6.
Echocardiography was used to determine the incidence and severity of cardiac lesions in 20 patients with progressive systemic sclerosis. Abnormal findings were recorded in 14 (70%) patients. These included pericardial effusion in five, increased right ventricular diameter in five, increased left ventricular posterior wall thickness in four with no systemic hypertension, decreased diastolic closure of anterior mitral leaflet in five, and abnormal septal features in four patients. Dilatation of aortic root was found in two patients and moderated thickening of the anterior mitral valve in one patient. Clinical evidence of scleroderma heart was found in one of the 20 patients. Abnormal ECG changes were found in 12 (60%) of the patients. These included LVH, simulating MI pattern, conduction disturbances and P wave changes. Echocardiography proved to be an important non-invasive diagnostic tool which decreases the discrepancy between the relatively few clinical findings and rich cardiac pathology. Furthermore, this study confirms the usefulness of the method in the evaluation of the "asymptomatic" cardiac patient.
超声心动图用于确定20例进行性系统性硬化症患者心脏病变的发生率和严重程度。14例（70%）患者有异常发现。这些异常包括5例心包积液、5例右心室直径增加、4例无系统性高血压但左心室后壁厚度增加、5例二尖瓣前叶舒张期关闭减弱以及4例患者的室间隔特征异常。2例患者发现主动脉根部扩张，1例患者二尖瓣前叶中度增厚。20例患者中有1例有硬皮病心脏的临床证据。12例（60%）患者有异常心电图改变。这些改变包括左心室肥厚、类似心肌梗死图形、传导障碍和P波改变。超声心动图被证明是一种重要的非侵入性诊断工具，它减少了相对较少的临床发现与丰富的心脏病理学之间的差异。此外，本研究证实了该方法在评估“无症状”心脏病患者中的有用性。
