DePierre J W, Seidegård J, Morgenstern R, Balk L, Meijer J, Aström A, Norélius I, Ernster L
Xenobiotica. 1984 Apr;14(4):295-301. doi: 10.3109/00498258409151415.
The effects of treating male Sprague-Dawley rats with phenobarbital, 3-methylcholanthrene or trans-stilbene oxide on cytosolic glutathione transferase and microsomal epoxide hydrolase activities in the liver, intestine, kidney, lung, testis, adrenal, spleen, heart and brain have been investigated. Studies on the time-courses of induction in liver demonstrate that these are complete after five days' treatment at the doses used. Phenobarbital induces both cytosolic glutathione transferase and microsomal epoxide hydrolase activities significantly only in liver and intestine. 3-Methylcholanthrene induces these activities in liver only. Trans-Stilbene oxide induces both of these activities in liver and kidney, and cytosolic glutathione transferase activity in adrenal as well.
研究了用苯巴比妥、3-甲基胆蒽或反式氧化茋处理雄性斯普拉格-道利大鼠后，其肝脏、肠道、肾脏、肺、睾丸、肾上腺、脾脏、心脏和大脑中胞质谷胱甘肽转移酶和微粒体环氧化物水解酶活性的变化。对肝脏诱导时间进程的研究表明，在所使用的剂量下，处理五天后诱导作用完全。苯巴比妥仅显著诱导肝脏和肠道中的胞质谷胱甘肽转移酶和微粒体环氧化物水解酶活性。3-甲基胆蒽仅诱导肝脏中的这些活性。反式氧化茋诱导肝脏和肾脏中的这两种活性，以及肾上腺中的胞质谷胱甘肽转移酶活性。
