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[大蒜提取物的急性毒性试验]

[Acute toxicity test of garlic extract].

作者信息

Nakagawa S, Masamoto K, Sumiyoshi H, Harada H

出版信息

J Toxicol Sci. 1984 Feb;9(1):57-60. doi: 10.2131/jts.9.57.

Abstract

The acute toxicity toxicity test of garlic extract was studied in Wistar rats and ddY mice. The LD50 values of garlic extract by P.O., I.P. and S.C. administration were estimated over 30 ml/kg respectively in male and female of both rodents. In 30 ml/kg of I.P. group, five of ten in male rats and one of ten in female rats were died within a day after administration, however no specific signs due to garlic extract were observed in survivals for 7 days.

摘要

在Wistar大鼠和ddY小鼠中研究了大蒜提取物的急性毒性试验。通过口服、腹腔注射和皮下注射给予大蒜提取物,两种啮齿动物的雄性和雌性LD50值估计均超过30 ml/kg。在腹腔注射30 ml/kg组中,雄性大鼠10只中有5只、雌性大鼠10只中有1只在给药后一天内死亡,然而在存活7天的动物中未观察到因大蒜提取物引起的特定体征。

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