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使用微型氧传感器进行术中器官灌注和活力评估的方法

Method for intraoperative assessment of organ perfusion and viability using a miniature oxygen sensor.

作者信息

Kram H B, Shoemaker W C

出版信息

Am J Surg. 1984 Sep;148(3):404-7. doi: 10.1016/0002-9610(84)90482-3.

Abstract

A specially designed miniaturized Clark polarographic electrode was used to measure organ surface oxygen tension during surgical operations in 10 patients as a means of determining tissue perfusion and viability. When applied to organ surfaces, the sensor noninvasively provides real-time assessment of tissue PO2. Values obtained are dependent on both arterial PO2 and local blood flow and therefore may be used to quantitatively assess local oxygen delivery (perfusion). Measured values may be compared with arterial PO2 or to areas of certain normal perfusion on the same organ to better define the adequacy of local oxygen transport. Tissue temperature is independently measured and may be used to assess the metabolic activity of the tissue monitored. Organ surface oximetry using the miniature PO2 sensor is a practical and repeatable method for the intraoperative assessment of organ perfusion and viability.

摘要

一种专门设计的小型化克拉克极谱电极被用于测量10例患者手术过程中器官表面的氧张力,以此作为确定组织灌注和活力的一种手段。当应用于器官表面时,该传感器可无创地实时评估组织的氧分压。所获得的值取决于动脉氧分压和局部血流,因此可用于定量评估局部氧输送(灌注)。测量值可与动脉氧分压或同一器官上某些正常灌注区域进行比较,以更好地确定局部氧转运的充足性。独立测量组织温度,并可用于评估所监测组织的代谢活性。使用微型氧分压传感器进行器官表面血氧测定是一种用于术中评估器官灌注和活力的实用且可重复的方法。

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