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小鼠雄性生殖细胞减数分裂的过早启动。

Precocious initiation of meiosis by male germ cells of the mouse.

作者信息

Ozdzenski W, Presz M

出版信息

Arch Anat Microsc Morphol Exp. 1984;73(1):1-7.

PMID:6476834
Abstract

12 1/2-15 1/2 day embryonic mouse testes of 129/terSv and CBA/T6T6 strains were transplanted under the kidney capsule of adult hosts. After 3-5 days in 41% of CBA/T6T6 transplants and in 82% of 129/terSv transplants a limit number of germ cells began meiosis. The percentage of meiotic germ cells was inversely related to the total number of gonocytes and the organization of seminiferous cords. The presented evidence indicates that the ability of the germ cells to begin meiosis precociously depends on: 1) genotype of donor embryos; 2) age of transplanted testis, and 3) using whole of half of gonad for transplantation. After 10-15 days in two out of 46 129/terSv testes (4%) growing oocytes were observed.

摘要

将129/terSv和CBA/T6T6品系的12.5 - 15.5天胚胎期小鼠睾丸移植到成年宿主的肾被膜下。3 - 5天后,41%的CBA/T6T6移植睾丸和82%的129/terSv移植睾丸中,有限数量的生殖细胞开始减数分裂。减数分裂生殖细胞的百分比与生殖母细胞总数和生精索的组织结构呈负相关。现有证据表明,生殖细胞早熟开始减数分裂的能力取决于:1)供体胚胎的基因型;2)移植睾丸的年龄;3)移植时使用整个性腺还是半个性腺。10 - 15天后,在46个129/terSv睾丸中的2个(4%)观察到正在生长的卵母细胞。

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