Patarasakulchai N, Southwell-Keely P T
Biochem J. 1984 Aug 1;221(3):797-801. doi: 10.1042/bj2210797.
Se-Aryl selenenylthiosulphates and S-aryl sulphenylthiosulphates inhibit papain at pH 5.8 much more rapidly than do the corresponding Se-aryl selenosulphates and S-aryl thiosulphates, and also more rapidly than do Se-alkyl selenosulphates. Se-p-Nitrophenyl selenenylthiosulphate and S-p-nitrophenyl sulphenylthiosulphate inactivate papain most rapidly, but the inactivation is slowly and spontaneously reversible. Inactivation by Se-o-nitrophenyl selenenylthiosulphate and S-o-nitrophenyl sulphenylthiosulphate, although less rapid than that by the para isomers, is essentially irreversible.
硒芳基硒代硫代硫酸盐和硫芳基硫代亚磺酸盐在pH 5.8时抑制木瓜蛋白酶的速度比相应的硒芳基亚硒酸盐和硫芳基硫代硫酸盐快得多，也比硒烷基亚硒酸盐快。对硝基苯硒代硫代硫酸盐和对硝基苯硫代亚磺酸盐使木瓜蛋白酶失活最快，但失活是缓慢且自发可逆的。邻硝基苯硒代硫代硫酸盐和邻硝基苯硫代亚磺酸盐引起的失活虽然比对位异构体慢，但基本上是不可逆的。
