在给饥饿的MPC-11细胞喂食后，轻糙面内质网膜比重糙面内质网膜先重新出现。

Light rough endoplasmic reticulum membranes re-appear before heavy rough membranes after feeding starved MPC-11 cells.

作者信息

Pryme I F

出版信息

Biochem Int. 1984 May;8(5):647-54.

Abstract

In 48 hr starved MPC-11 cells smooth (S) endoplasmic reticulum (ER) membranes accounted for more than 80% of the total ER membrane fraction. After 2 1/2 hr feeding the amount of S membranes was reduced to below 55% while light rough (LR) membranes had increased from about 16% of the total to 42%. The percentage of heavy rough (HR) membranes only showed a minor increase during the incubation period. The results show that following an accumulation of S membranes in starved cells the LR membranes 're-appear' more rapidly than the HR membranes. This difference in behaviour provides further support to the concept that LR and HR membranes represent distinct domains of the ER system.

摘要

在饥饿48小时的MPC-11细胞中，光滑（S）内质网（ER）膜占内质网膜总组分的80%以上。喂食2个半小时后，S膜的量减少到55%以下，而轻度粗面（LR）膜则从约占总量的16%增加到42%。重度粗面（HR）膜的百分比在孵育期间仅略有增加。结果表明，在饥饿细胞中S膜积累后，LR膜比HR膜“重新出现”得更快。这种行为差异进一步支持了LR膜和HR膜代表内质网系统不同区域的概念。

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