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[米勒-费希尔综合征:一例报告]

[Miller Fisher syndrome: report of a case].

作者信息

Resende L A, Battistuta R J, Sato T, De Bortoli N A

出版信息

Arq Neuropsiquiatr. 1984 Jun;42(2):171-4. doi: 10.1590/s0004-282x1984000200011.

Abstract

The authors report a case of a 27 year old male patient who has exhibited external ophthalmoplegia, anisocoria, ataxia, absent deep reflexes, dysphagia, dysphonia, bilateral peripheral facial paralysis, hypopallesthesia and a mild sensory impairment of the four extremities. In addition, his cerebrospinal fluid showed albuminocytologic dissociation. The otoneurologic examination showed important findings. These symptoms began ten days after a "cold", and quickly subsided after prednisone therapy. Two months after the onset of clinical features, just a deep apendicular areflexia was detected on his neurological examination. The neurological signs and complementary laboratory findings suggest that both central and peripheral alterations are responsible for the clinical manifestations.

摘要

作者报告了一例27岁男性患者,该患者出现了眼球外肌麻痹、瞳孔不等大、共济失调、深部反射消失、吞咽困难、发音障碍、双侧周围性面瘫、轻触觉减退以及四肢轻度感觉障碍。此外,他的脑脊液显示蛋白细胞分离。耳神经学检查有重要发现。这些症状在“感冒”后十天开始出现,泼尼松治疗后迅速消退。临床症状出现两个月后,其神经学检查仅发现深部肢体反射消失。神经体征和辅助实验室检查结果表明,中枢和外周改变均导致了临床表现。

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