Applegate W B, Graves S, Collins T, Vander Zwaag R, Akins D
South Med J. 1984 Sep;77(9):1127-9. doi: 10.1097/00007611-198409000-00018.
We conducted a retrospective chart review on 50 patients under age 65 (average age 52.9 years) and 55 patients over 65 (average age 75.6 years). The older patients were much more likely to have atypical pain or no pain (38% vs 4%, P less than .0001). They were less likely to have electrocardiographic QRS changes (47% vs 72%), but more likely to have congestive heart failure (44% vs 16%, P less than .01). In 25% of the older patients, no diagnosis was made in the first 24 hours, as compared to 8% of the younger group. The increased mortality in the older group (16% vs 4%) approached statistical significance (P = .08). We conclude that the manifestations of acute myocardial infarction are more subtle in the elderly, with a higher proportion of atypical chest pain and nondiagnostic electrocardiograms, but the elderly are more likely to have congestive heart failure.
我们对50名65岁以下患者(平均年龄52.9岁)和55名65岁以上患者(平均年龄75.6岁)进行了回顾性病历审查。老年患者更有可能出现非典型疼痛或无疼痛(38%对4%,P<0.0001)。他们出现心电图QRS改变的可能性较小(47%对72%),但发生充血性心力衰竭的可能性较大(44%对16%,P<0.01)。25%的老年患者在最初24小时内未确诊,而年轻组这一比例为8%。老年组死亡率增加(16%对4%)接近统计学显著性(P = 0.08)。我们得出结论,急性心肌梗死在老年人中的表现更为隐匿,非典型胸痛和非诊断性心电图的比例更高,但老年人发生充血性心力衰竭的可能性更大。