抗坏血酸盐对反应混合物中亚硝酸钠浓度自发降低的体外作用。
An in vitro effect of ascorbate on the spontaneous reduction of sodium nitrite concentration in a reaction mixture.
作者信息
Basu T K, Weiser T, Dempster J F
出版信息
Int J Vitam Nutr Res. 1984;54(2-3):233-6.
PMID:6500848
Abstract
Nitrite is known to react with free amines to form nitrosamines which may have carcinogenic activity. The present study provides evidence showing that addition of ascorbic acid in a reaction mixture results in a spontaneous decrease in nitrite concentration. The nitrite lowering effect of ascorbic acid appears to correlate with the rate of oxidation of the vitamin to dehydroascorbic acid, suggesting that ascorbic acid may be involved in the reduction of nitrite to nitrogen oxide.
摘要
已知亚硝酸盐会与游离胺反应生成可能具有致癌活性的亚硝胺。本研究提供的证据表明，在反应混合物中添加抗坏血酸会导致亚硝酸盐浓度自发降低。抗坏血酸的亚硝酸盐降低作用似乎与维生素氧化为脱氢抗坏血酸的速率相关，这表明抗坏血酸可能参与了将亚硝酸盐还原为氮氧化物的过程。
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