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葡萄糖-6-磷酸脱氢酶再探讨。

Glucose-6-phosphate dehydrogenase revisited.

作者信息

O'Connell J T, Henderson A R

出版信息

J Natl Med Assoc. 1984 Nov;76(11):1135-6, 1139, 1143.

Abstract

Hemolytic diseases associated with drugs have been recognized since antiquity. Many of these anemias have been associated with oxidizing agents and deficiencies in the intraerythrocytic enzyme glucose-6-phosphate dehydrogenase. This paper outlines the discovery, prevalence, and variants of this enzyme. Methods of diagnosis of associated anemias are offered.

摘要

与药物相关的溶血性疾病自古以来就已被认识到。这些贫血症中有许多与氧化剂以及红细胞内葡萄糖-6-磷酸脱氢酶缺乏有关。本文概述了这种酶的发现、流行情况及变异型。文中还提供了相关贫血症的诊断方法。

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