Goldenberg G, Samec P
Wien Klin Wochenschr. 1984 Aug 3;96(15):569-76.
Statistical correlations were sought between the clinical data, the neurological signs and the results of angiography in 224 patients who had had panangiography for cerebral ischaemia. With advancing age there is an increase in the incidence of stenosis, but not of occlusion in the cervical portion of the carotid artery. Patients who suffer from peripheral or coronary occlusive artery disease have a higher incidence of stenosis and occlusion of the cervical carotid artery, but most are clinically silent. If there is a cardiac source of embolism, the main lesions are found in the middle cerebral artery. The frequency of middle cerebral artery branch occlusions is elevated in areas distal to stenosis and occlusion of the carotid artery. More than half of the patients whose neurological deficit augmented over a period exceeding one day have lesions in the cervical carotid artery. The degree of narrowing of the carotid or middle cerebral artery shows a negative correlation with neurological recovery, but in transient ischaemic attacks with recovery under one hour there is a high incidence of carotid artery stenosis. As to the neurologic symptoms there was a clear difference between the findings in medial cerebral artery ischaemia and those in vertebrobasilar ischaemia. Furthermore, the findings in the former condition show a positive correlation with the gravity of the deficit, whilst those of the vertebrobasilar artery correlate with the symptoms of a lacunar state. 9 of 10 patients with amaurosis fugax had lesions of the ipsilateral carotid artery.(ABSTRACT TRUNCATED AT 250 WORDS)
对224例因脑缺血接受全脑血管造影的患者的临床数据、神经体征与血管造影结果进行了统计学相关性分析。随着年龄增长,颈动脉颈部狭窄的发生率增加,但闭塞的发生率并未增加。患有外周或冠状动脉闭塞性动脉疾病的患者,颈动脉颈部狭窄和闭塞的发生率较高,但大多数在临床上无症状。如果存在心脏栓子来源,主要病变见于大脑中动脉。在颈动脉狭窄和闭塞远端区域,大脑中动脉分支闭塞的频率升高。超过一半的神经功能缺损持续超过一天的患者,其颈动脉有病变。颈动脉或大脑中动脉的狭窄程度与神经功能恢复呈负相关,但在一小时内恢复的短暂性脑缺血发作中,颈动脉狭窄的发生率较高。至于神经症状,大脑中动脉缺血和椎基底动脉缺血的表现有明显差异。此外,前一种情况的表现与缺损的严重程度呈正相关,而椎基底动脉的表现与腔隙状态的症状相关。10例一过性黑矇患者中有9例同侧颈动脉有病变。(摘要截选于250字)