Sikarskie D L, Stein P D, Vable M
J Biomech. 1984;17(11):831-7. doi: 10.1016/0021-9290(84)90141-6.
It has been shown experimentally that the second heart sound is produced by diastolic vibrations of the closed aortic valve. In the present paper a mathematical model of this vibration is developed from first principles. The model assumes a one dimensional but non-linear fluid behavior. The problem is coupled through a non-linear, planar valve. A solution is obtained using the method of characteristics developed in finite difference form. The resulting valve frequency and amplitude are in good agreement with patient data. The model predicts a strong dependency of response on the valve forcing function and valve stiffness; and a weaker dependency of response on valve mass.
实验表明,第二心音是由关闭的主动脉瓣的舒张期振动产生的。在本文中,从基本原理出发建立了这种振动的数学模型。该模型假设流体行为是一维但非线性的。该问题通过一个非线性平面瓣膜进行耦合。使用以有限差分形式发展的特征线法获得了一个解。所得的瓣膜频率和振幅与患者数据吻合良好。该模型预测响应强烈依赖于瓣膜强迫函数和瓣膜刚度;而响应较弱依赖于瓣膜质量。