Boffa C, Merisio M G, Rivolta S, Fontanelli G, Franchi E, Terzoli S, Stucchi C
Pediatr Med Chir. 1984 Nov-Dec;6(6):755-8.
We discuss 25 cases of death observed from 1971 to 1983 in a casistic of 155 patients with Thalassaemic Syndrome. Anemia as a cause of death is disappearing, new triggers are involved such as Yersinia Enterocolitica who can cause severe sepsis even in non-splenectomized patients. Iron overload appears to be the most severe complication in the second decade.
我们讨论了1971年至1983年期间在155例地中海贫血综合征患者病例中观察到的25例死亡情况。贫血作为死亡原因正在消失,新的诱因出现了,比如小肠结肠炎耶尔森菌,即使在未行脾切除术的患者中也可导致严重败血症。铁过载似乎是第二个十年中最严重的并发症。