de Heer K, Schnippenkoetter I, Kortmann K B, Beeger R
Chirurg. 1984 Mar;55(3):171-3.
In a follow-up study of 112 patients who had subtotal thyroidectomy because of Graves' disease and nodular goitre with hyperthyroidism, 81% were euthyroid, 10,7% developed hypothyroidism and 8% had persistent or recurrent hyperthyroidism. 12,5% of the euthyroid patients had goitre; 10 of these patients had cold thyroid nodules. The assessment of the dignity of the cold nodules and guidelines for the therapeutic procedure are stressed. The importance of considering clinical findings on one hand and thyroid function tests on the other hand in the choice of effective treatment - prophylaxis against euthyroid goitre, substitution with hormones, iodine-131 therapy, antithyroid drugs or reoperation - is outlined.
在一项对112例因格雷夫斯病和结节性甲状腺肿伴甲状腺功能亢进而行甲状腺次全切除术患者的随访研究中,81%的患者甲状腺功能正常,10.7%的患者出现甲状腺功能减退,8%的患者持续或复发甲状腺功能亢进。甲状腺功能正常的患者中有12.5%存在甲状腺肿;其中10例患者有冷甲状腺结节。强调了对冷结节性质的评估及治疗程序指南。概述了在选择有效治疗方法(预防甲状腺功能正常的甲状腺肿、激素替代、碘-131治疗、抗甲状腺药物或再次手术)时,一方面考虑临床发现,另一方面考虑甲状腺功能测试的重要性。