Frankshtein S I, Sergeeva Z N, Sergeeva T I
Biull Eksp Biol Med. 1978 Apr;85(4):395-7.
A restricted damage of the lung parenchyma before vagotomy evokes an increase of inspiratory discharges of the diaphragm and an increase of the rate of respiration. Similar damage in vagotomized animals evokes only an increase of inspiratory discharges. The rate of respiration does not alter at all or changes insignificantly. An increase of the depth of respiration evoked by the lung nociceptors innervated by the extravagal afferents is of great importance because the lung ventilation is best provided by deep respiration. Probably not only the afferent fibers of the vagus nerves, but also the extravagal lung afferents must be taken into consideration in analysis of the relationship between the rate and depth of lung ventilation, particularly under pathological conditions.
迷走神经切断术前肺实质的局限性损伤会引起膈肌吸气放电增加和呼吸频率加快。在迷走神经切断的动物中，类似损伤仅引起吸气放电增加。呼吸频率根本不变或仅有轻微变化。由迷走神经外传入纤维支配的肺伤害感受器引起的呼吸深度增加非常重要，因为深呼吸能最佳地提供肺通气。在分析肺通气的速率和深度之间的关系时，尤其是在病理情况下，可能不仅要考虑迷走神经的传入纤维，还必须考虑迷走神经外的肺传入纤维。
