Tsai S H, Lin S Z, Shih C J
Proc Natl Sci Counc Repub China B. 1984 Oct;8(4):335-40.
The preventive effect of pre-ganglionic decentralization (Sympathetic trunk resectioN) or postganglionic excision (ganglionectomy) of the superior cervical ganglia on thermal injury induced brain edema or the development of heat stroke was assessed in rats. Brain edema was induced by cold or heat injury to the cortex in 24 rats. The results showed that decentralization, but not excision, of the superior cervical ganglia greatly inhibited the formation of brain edema which was subsequently induced. When heat stroke was induced by exposing 24 rats to an ambient temperature of 41 degree C, the latency for the onset of the heat stroke and the survival time after the heat stroke were greatly prolonged by the former surgical procedure, but shortened by the later one. The present study demonstrates the potential benefit to brain edema and heat stroke of the pretreatment with decentralization of the superior cervical ganglia.
在大鼠中评估了颈上神经节的节前去神经支配（交感干切除术）或节后切除（神经节切除术）对热损伤诱导的脑水肿或中暑发展的预防作用。对24只大鼠的皮质进行冷或热损伤以诱导脑水肿。结果表明，颈上神经节的去神经支配而非切除，极大地抑制了随后诱导的脑水肿的形成。当将24只大鼠暴露于41摄氏度的环境温度中诱导中暑时，前一种手术程序可大大延长中暑发作的潜伏期和中暑后的存活时间，而后一种手术程序则会缩短这些时间。本研究证明了颈上神经节去神经支配预处理对脑水肿和中暑的潜在益处。
