颅面发育：某些畸形的可能机制。

Craniofacial development: the possible mechanisms for some malformations.

作者信息

Vig K W, Millicovsky G, Johnston M C

出版信息

Br J Orthod. 1984 Jul;11(3):114-8. doi: 10.1179/bjo.11.3.114.

DOI:10.1179/bjo.11.3.114

PMID:6591949

Abstract

Normal craniofacial development is reviewed and some mechanisms in the fusion of mammalian facial 'processes' are discussed. The manipulation of environmental factors and effects of teratogens are related to genetic susceptibility of animal models, and extrapolated to craniofacial malformations in man.

摘要

本文综述了正常的颅面发育过程，并讨论了哺乳动物面部“突起”融合的一些机制。环境因素的操控和致畸剂的影响与动物模型的遗传易感性相关，并外推至人类的颅面畸形。