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[口服氢氟酸烟醇后人体中氟的血液药代动力学]

[Blood pharmacokinetics of fluorine in man after the oral administration of nicomethanol hydrofluoride].

作者信息

Cheymol G, Souleau M, Mahuzier G, Poitou P

出版信息

J Biol Buccale. 1984 Dec;12(4):349-53.

PMID:6597190
Abstract

The pharmacokinetic parameters of fluoride have been studied, after a single oral administration to human volunteers of two fluoridated compounds: sodium fluoride, and a new organic fluoride salt, nicomethanol hydrofluoride. The results obtained with these two compounds were very similar, suggesting that no abnormal accumulation of fluoride in the body occurs after using nicomethanol hydrofluoride.

摘要

在向人类志愿者单次口服两种含氟化合物(氟化钠和一种新型有机氟盐氢氟尼考甲醇)后,对氟化物的药代动力学参数进行了研究。用这两种化合物获得的结果非常相似,这表明使用氢氟尼考甲醇后,体内不会出现氟化物异常蓄积的情况。

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