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[获得性免疫缺陷综合征、机会性感染和卡波西肉瘤:一种新疾病的流行]

[Acquired immune deficiency syndrome, opportunistic infections and Kaposi's sarcoma: epidemic of a new disease].

作者信息

Francioli P

出版信息

Schweiz Med Wochenschr. 1983 Jul 2;113(26):938-42.

PMID:6604313
Abstract

During the last two years a new syndrome has been recognized which involves a severe acquired cellular immunodeficiency. More than 1300 cases have already been identified, mainly in the United States. Clinically the patients present with opportunistic infections, especially Pneumocystis carinii pneumonia, and/or tumors (often a Kaposi sarcoma). Frequently this is preceded by a prodromal phase with fever, weight loss and lymphadenopathies. The overall mortality is over 40% and may reach 100%. Groups at risk for the syndrome are male homosexuals, i.v. drug abusers. Haitians, possibly some Africans and patients who have received blood products. These epidemiologic data suggest that the syndrome is probably due to a bloodtransmitted infectious agent.

摘要

在过去两年中,一种新的综合征被确认,它涉及严重的后天性细胞免疫缺陷。已经确诊了1300多例,主要在美国。临床上,患者表现为机会性感染,尤其是卡氏肺孢子虫肺炎和/或肿瘤(通常是卡波西肉瘤)。在此之前,患者常常会经历一个前驱期,伴有发热、体重减轻和淋巴结病。总体死亡率超过40%,甚至可能达到100%。该综合征的高危人群包括男性同性恋者、静脉注射毒品者、海地人、可能还有一些非洲人以及接受过血液制品的患者。这些流行病学数据表明,该综合征可能是由一种血液传播的传染因子引起的。

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